[Comparison of effectiveness of liquid nitrogen and podophyllin in treatment of genital warts in males]

Clinical assessment of effectiveness of liquid nitrogen and podophyllin in treatment of genital warts, and comparison of the two treatments in clearance and recurrence rates. Forty male patients [19 to 53 years old] were allocated to receive treatment for genital warts; they were randomly divided into two groups; liquid nitrogen group and podophyllin group. Therapy was continued for 6 weeks. After that the patients were assessed for clearance of lesions, and then monitored for recurrence for three months after clearance of lesions. In the first group [liquid nitrogen] lesions cleared in 75% of patients, and there was a recurrence in 33% of the cured patients during first 3 months. While in the second group [podophyllotoxin], lesions cleared in 30% of patients, and recurrence occurred in 43% of those patients. There was a statistical significant difference [p=0.05] between clearance rates in the two groups, whereas the difference wasn't statistically significant between recurrence rates. Cryotherapy [liquid nitrogen] showed more efficacy than podophyllin 20% in treatment of genital warts in males, with no difference in clearance rates

Compromiso testicular en púrpura de Schõnlein Henoch, utilidad de la ecotomografía doppler / Testicular involvement in Henoch-Schõnlein purpura: the useful of doppler sonography

El púrpura de Schõnlein Henoch (PSH) es la vasculitis más frecuente de la infancia; afecta principalmente la piel, articulaciones y sistema gastrointestinal. El compromiso de los testículos se observa en el 15 por ciento de los pacientes, pero es raro como forma de presentación (1-2 por ciento). El presente caso clínico describe un niño de 4 años de edad sin antecedentes mórbidos que consultó por dolor, eritema, aumento de volumen testicular derecho y púrpura palpable de extremidades inferiores, cuya ecografía testicular mostró testículos normales con flujo Doppler normal y aumento de grosor de escroto y cordón espermático ipsi lateral. Exámenes de laboratorio fueron normales. Se diagnosticó PSH con compromiso testicular y se trató exitosamente con corticoides orales por una semana. Es importante considerar esta patología como diagnóstico diferencial de testículo agudo, para evitar la exploración quirúrgica innecesaria. Las características ecográficas permiten confirmar la sospecha diagnóstica.

Henoch Schõnlein purpura is the most common vasculitis presenting in the childhood, with frequent skin, articular and gastrointestinal compromise. Testicular pain is rare as an onset symptom (1-2 percent), but 15 percent of the cases develop it during the illness course. This case report describes a previously healthy 4 year old boy, who was admitted in theemergency department with a painful, erythematous right scrotal swelling, associated with palpable purpura on both inferior extremities. Testicular Color Doppler US imagingout ruled testicular alterations, but the ipsilateral scrotum and spermatic cord were enlarged. Blood was drawn for serologic and hematologic testing with normal results. Shõnlein Henoch purpura with testicular involvement was diagnosed and successfully treated with oral corticosteroids for one week. It is important to consider Schõnlein Henoch purpura among the differential diagnosis of acute testicle in order to avoid unnecessary surgical exploration. Testicular Doppler Ultrasound imaging is recommended to confirm the diagnosis.